Activités de Recherche : 

Mes activités de recherche concernent le rôle de l’UPR (Unfolded Protein Response) et des processus red−ox dans les interactions plantes-microorganismes. Une autre partie de mon activité concerne l’étude de l’effet des pesticides dont les stimulateurs de défense des plantes sur des organismes non-cibles. Elle est réalisée en collaboration avec une équipe de l'unité INSERM 1231 de Dijon et avec le pôle MICSOL de l’UMR Agroécologie

Activités d’enseignement  : 

Dans le cadre de mes activités,  je participe à l’enseignement à l’Université de Bourgogne :

- Biotechnologies Végétales. Licence3 biologie, UFR SVTE, Univ. Bourgogne. CM/TD/TP

- Bioinformatique. Licence 3 de biologie, UFR SVTE, Univ. Bourgogne. TP

- Biotechnologies végétales. BUT3, IUT de Dijon. CM/TD/TP, responsable de l’UE

- Biologie cellulaire. BUT1, IUT de Dijon. TP

- Physiologie végétale. M1 Vigne, Vin, Terroir. Institut de la Vigne et du Vin. TD/TP.

Publications :

36. Mortier E, Mounier A, Kreplak J, Martin-Laurent F, Recorbet G and Lamotte O (2023) Evidence that a common arbuscular mycorrhizal network alleviates phosphate shortage in interconnected walnut sapling and maize plants. Front. Plant Sci. 14:1206047. doi: 10.3389/fpls.2023.1206047

35. Nguyen NN, Lamotte O, Alsulaiman M, Ruffel S, Krouk G, Berger N, Demolombe V, Nespoulous C, Dang TMN, Aimé S, Berthomieu P, Dubos C, Wendehenne D, Vile D, Gosti F (2023) Reduction in PLANT DEFENSIN 1 expression in Arabidopsis thaliana results in increased resistance to pathogens and zinc toxicity. J. Exp. Bot., erad228, https://doi.org/10.1093/jxb/erad228

34. Mortier E., Jacquiod S., Jouve J., Martin-Laurent F., Recorbet G., Lamotte O. (2023) Micropropagated walnut dependency on phosphate fertilization and arbuscular mycorrhiza for growth, nutrition and quality differ between rootstocks both after acclimatization and post-acclimatization. Scientia Horticulturae. 318, 112081. https://doi.org/10.1016/j.scienta.2023.112081.

33. Boll E., Cantrelle F.X., Lamotte O., Aimé S., Wendehenne D. and Trivelli X. (2022) 1H, 13C, and 15N chemical shift backbone resonance NMR assignment of Tobacco Calmodulin2. Biomolecular NMR Assignments 16 : 63-66. https://doi.org/10.1007/s12104-021-10060-5

32. Mortier E., Lamotte O., Martin-Laurent F. and Recorbet G. (2020) Walnut relationships with arbuscular mycorrhizal fungi as related to root traits, seedling quality and cultural practices: a review. Agronomy for Sustainable Development 40, Article number: 43  https://doi.org/10.1007/s13593-020-00647-y

31. Teyssier L., Sorci G., Chluba J., Aimé S., Wendehenne D., Lamotte O. and Connat JL. (2020) Some Plant Defense Stimulators can induce IL-1β production in human immune cells in vitro. Toxicology Reports 7:413-420. doi.org/10.1016/j.toxrep.2020.02.013

30. Aimé S., Hichami S., Wendehenne D. and Lamotte O. (2018) Analysis of Recombinant Protein S-Nitrosylation Using the Biotin-Switch Technique. Methods Mol Biol. 1747:131-141. doi: 10.1007/978-1-4939-7695-9_11.

29. Nicolas-Francès V., Grandperret V., Liegard B., Jeandroz S., Vasselon D., Aimé S., Klinguer A., Lamotte O., Julio E., Dorlhac de Borne F., Wendehenne D. and Bourque S. (2018) Evolutionary diversification of type-2 HDAC structure, function and regulation in Nicotiana tabacum. Plant Science 269:66-74. doi: 10.1016/j.plantsci.2018.01.007.

28.  Jeandroz S. and Lamotte O. (2017) Editorial : Plant responses to biotic and abiotic stresses: lessons from cell signaling. Front. Plant Sci. doi: 10.3389/fpls.2017.01772

27. Teyssier L., Colussi J., Delemasure S., Chluba J., Wendehenne D., Lamotte O*. and Connat J.-L*. (2017) Inflammatory Effects of the Plant Protection Product Stifenia (FEN560) on Vertebrates. Front. Public Health 5:74. doi: 10.3389/fpubh.2017.00074 (*corresponding author)

26. Claverie J., Teyssier L., Héloir M.-C., Connat J.-L., Lamotte O.* and Poinssot B.* (2016) Les plantes possèdent un système immunitaire efficace pour lutter contre les infections bactériennes Med Sci (Paris) 32 : 335-339. doi: 10.1051/medsci/20163204008 (*corresponding author)

25. Lamotte O., Bertoldo J.B., Besson-Bard A., Rosnoblet C, Aimé S., Hichami S., Terenzi H. and Wendehenne D. (2015) Protein S-nitrosylation: specificity and identification strategies in plants. Front Chem. doi: 10.3389/fchem.2014.00114 

24. Trapet P., Kulik A., Lamotte O., Jeandroz S., Bourque S., Nicolas-Francès V., Rosnoblet C., Besson-Bard A., Wendehenne D. (2015) NO signaling in plant immunity: A tale of messengers. Phytochemistry 112 : 72-79. doi: 10.1016/j.phytochem.2014.03.015

23. Jeandroz S., Lamotte O., Astier J., Rasul S., Trapet P., Besson-Bard A., Bourque S., Nicolas-Frances V., Wei M.,  Berkowitz G., and Wendehenne D. (2013) There's more to the picture than meets the eye: Nitric oxide cross-talk with Ca2+ signaling. Plant Physiol. 163 : 459-470. doi: 10.1104/pp.113.220624

22. Koen E., Besson-Bard A., Duc C., Astier J., Gravot A., Richaud P., Lamotte O., Boucherez J., Gaymard F., Wendehenne D. (2013) Arabidopsis thaliana nicotianamine synthase 4 is required for proper response to iron deficiency and to cadmium exposure. Plant Sci. 209 : 1-11. doi: 10.1016/j.plantsci.2013.04.006

21. Koen E., Lamotte O., Besson-Bard A., Bourque S., Nicolas-Frances V., Jeandroz S., and Wendehenne D. (2013) Nitric oxide is a major player in plant immune system. Méd. Sci. 29 : 309-316. doi: 10.1051/medsci/2013293018

20. Doidy J., van Tuinen D., Lamotte O., Corneillat M., Alcaraz G., and Wipf D (2012) The Medicago truncatula sucrose transporter family. Characterization and implication of key members in carbon partitioning towards arbuscular mycorrhizal fungi. Mol. Plant, 5 : 1346-1358. doi: 10.1093/mp/sss079

19. Astier J., Besson-Bard A., Lamotte O., Bourque S., Bertoldo J., Terenzi H. and Wendehenne D. (2012) NO inhibits the ATPase activity of the chaperone-like AAA+ATPase CDC48, a target for S- nitrosylation in cryptogein signaling in tobacco cells, Biochem. J., 5 : 1346-1358. DOI: 10.1042/BJ20120257

18. Astier J., Kulik A., Koen E., Besson-Bard A., Bourque S., Jeandroz S., Lamotte O. and  Wendehenne D. (2012) Protein S-nitrosylation: What's going on in plants? Free Radic. Biol. Med.,53 : 1101-1110. doi: 10.1016/j.freeradbiomed.2012.06.032

17. Rasul S., Dubreuil-Maurizi C., Lamotte O., Koen E., Poinssot B., Alcaraz G., Wendehenne D. and Jeandroz S. (2012) Nitric oxide production mediates oligogalacturonides-triggered immunity and resistance to Botrytis cinerea in Arabidopsis thaliana. Plant Cell Environ., 35 : 1483-1499. https://doi.org/10.1111/j.1365-3040.2012.02505.x

16. La Camera S., L'Haridon F., Astier J., Zander M., Abou-Mansour E., Page G., Thurow C., Wendehenne D., Gatz C, Métraux J-P. and Lamotte O. (2011) The glutaredoxin ATGRXS13 is required for Arabidopsis susceptibility to the necrotrophic fungus Botrytis cinerea. Plant J., 68, 507-519. doi: 10.1111/j.1365-313X.2011.04706.x

15. L'Haridon F., Besson-Bard A., Binda M., Serrano M., Abou-Mansour E., Balet F., Schoonbeek H-J., Hess S., Mir R., Léon J., Lamotte O. and Métraux J-P. (2011) A permeable cuticle is associated with the release of reactive oxygen species and induction of innate immunity. PLoS Pathog., 7(7):e1002148. doi: 10.1371/journal.ppat.1002148.

14. Astier J., Rasul S., Koen E., Manzoor H., Besson-Bard A., Lamotte O., Jeandroz S., Durner J., Lindermayr C. and Wendehenne D. (2011) S-nitrosylation: an emerging post-translational protein modification in plants. Plant Sci., 181: 527-533. doi: 10.1016/j.plantsci.2011.02.011

13.Mazars C., Thuleau P., Lamotte O. and Bourque S. (2010) Cross-talk between ROS and calcium in regulation of nuclear activities. Mol. Plant, 3 : 706-718. doi: 10.1093/mp/ssq024

12. Zander M. , La Camera S., Lamotte O., Métraux J.-P. And Gatz C. (2010) Arabidopsis thaliana class- II TGA transcription factors are essential activators of jasmonic acid/ethylene-induced defense responses. Plant J., 61 : 200-210. doi: 10.1111/j.1365-313X.2009.04044.x

11. Chassot C., Buchala A., Schoonbeek H.-J., Métraux J.-P. and Lamotte O.* (2008) Wounding causes a powerful but transient protection against a major plant pathogen. Plant J., 55 : 555-567. doi: 10.1111/j.1365-313X.2008.03540.x.

10. Gauthier A., Lamotte O., Reboutier D., Bouteau F., Pugin A. and Wendehenne D. (2007) Cryptogein-induced anion effluxes : electrophysiological properties and analysis of the mechanisms through which they contribute to the elicitor-triggered cell death, Plant Signal. Behav., 2 : 86-95. PMID: 19516973

9. Garcia-Brugger A., Lamotte O., Vandelle C., Bourque S., Lecourieux D., Poinsot B., Wendehenne D. and Pugin A. (2006) Signaling pathways activated by elicitors of plant defenses. Mol. Plant Microbe Interact., 19 : 711-724. DOI:10.1094/MPMI-19-0711

8. Lamotte O., Courtois C., Dobrowolska G., Besson A., Pugin A. and Wendehenne D. (2006) Mechanisms of nitric oxide-induced increase of free cytosolic Ca2+ concentration in Nicotiana plumbaginifolia cells. Free Radic. Biol. Med., 40 : 1369-1376.  DOI :10.1016/j.freeradbiomed.2005.12.006

7. Wendehenne D., Gould K., Lamotte O., Durner J., Vandelle E., Lecourieux D., Courtois C., Barnavon L., Bentéjac M. and Pugin A. (2005) NO signaling functions in the biotic and abiotic stress responses. BMC Plant Biology 5 (Suppl 1) :S35 https://doi.org/10.1186/1471-2229-5-S1-S35

6. Lecourieux D., Lamotte O., Bourque S., Wendehenne D., Mazars C., Ranjeva R. and Pugin A. (2005) Proteinaceous and oligosaccharidic elicitors induce different calcium signatures in the nuclear of tobacco cells. Cell Calcium, 38 : 527-538. DOI:10.1016/j.ceca.2005.06.036

5. Lamotte O., Courtois C., Barnavon L., Pugin, A. and Wendehenne D. (2005) Nitric oxide in plants : the biosynthesis and cell signaling properties of a fascinating molecule. Planta, 221 : 1-4.

4. Lamotte O., Gould K., Lecourieux D., Sequeira-Legrand A., Klinguer A., Lebrun-Garcia A., Durner J., Pugin A. and Wendehenne D. (2004) Analysis of nitric oxide signaling functions in tobacco cells challenged by the proteinaceous elicitor cryptogein. Plant Physiol., 135 : 516-529. DOI: 10.1104/pp.104.038968

3. Gould K., Lamotte O., Klinguer A., Pugin A. and Wendehenne D. (2003) Nitric oxide production by tobacco leaves: a general stress responses? Plant cell environ., 26: 1851-1862. https://doi.org/10.1046/j.1365-3040.2003.01101.x

2. Wendehenne D., Lamotte O. and Pugin A. (2003) Plant iNOS: conquest of the Holy Grail. Trends Plant Sci., 8 : 465-468. DOI: 10.1016/j.tplants.2003.09.003

1. Wendehenne D., Lamotte O., Frachisse J-M., Barbier-Brygoo H. and Pugin A. (2002) Nitrate efflux is an essential component of the cryptogein signalling pathway leading to defense responses and hypersensitive cell death in tobacco. Plant Cell., 14 : 1937-1951. https://doi.org/10.1105/tpc.002295

Patent :

Cacas J.L., Vasselon D., Lamotte O., Poinssot B., Walker A.S. Utilisation de l’Acide 4-phénylbutyrique et/ou de l’Acide 3-phénylbutyrique et/ou de l’Acide 2-phénylbutyrique pour la Prévention et le Traitement des Maladies Cryptogamiques. AgroParisTech, CNRS, INRAe, Université de Bourgogne. 2021. WO2021233961 FR3110336.

Liens externes (Links) :

https://orcid.org/0000-0002-3721-3769

https://scholar.google.fr/citations?user=3nPDdD8AAAAJ&hl=fr

https://loop.frontiersin.org/people/195415/overview

https://hal.science/search/index/q/*/authIdHal_s/o-lamotte