Activités de recherche, techniques : 

Mes recherches se concentrent sur la compréhension des stratégies adaptatives des plantes face aux contraintes écologiques dans leur écosystème. J’utilise diverses approches expérimentales pour identifier les bases génétiques sous-tendant la réponse adaptative des plantes aux interactions biotiques complexes (ex., communautés de plantes et de pollinisateurs). Mes travaux au sein de l’UMR Agroécologie de Dijon ont pour but d’approfondir nos connaissances sur les légumineuses et leurs systèmes de culture dans une perspective agroécologique. J’emploie des approches d’associations génomiques (genome-wide association GWA, genome-environment association GEA) pour identifier les variants génétiques impliquées dans les interactions plante-plante (mono-variétales, pluri-variétales ou pluri-spécifiques). Ces travaux visent à intégrer les interactions plante-plante dans les programmes d’amélioration génétique des légumineuses.
 

Publications :

Dorey T., Frachon L., Rieseberg L.H., Kreiner J., Schiestl F.P. (2024) Biotic interactions promote local adaptation to soil in plants. Nature communications.

Kofler V.X., Grossniklaus U., Schiestl F., Frachon L. (2024) Uncovering genes involved in pollinator-driven mating system shifts and selfing syndrome evolution in Brassica rapa. New Phytologist.

Frachon L., Schiestl F.P. (2024) Rapid genomic evolution in Brassica rapa with bumblebee selection in experimental evolution. BMC Ecology and Evolution. 24: 7.

Roux F., Frachon L., Bartoli C. (2023) The Genetic Architecture of Adaptation to Leaf and Root Bacterial Microbiota in Arabidopsis thaliana. Molecular Biology and Evolution. 40: msad093

Frachon L., Arigo L., Rusman Q., Poveda L., Qi W., Scopece G. and Schiestl F.P. (2023) Putative signals of generalist plant species adaptation to local pollinator communities and abiotic factors. Molecular Biology and Evolution. 40: msad036

Roux F. and Frachon L. (2022) A genome-wide association study to decipher the adaptive genetics of in situ quantitative disease resistance in Arabidopsis thaliana. PLoS ONE.

Russo A., Mayjonade B., Frei D., Potente G., Kellenberger R.T., Frachon L., Copetti D., Studer B., Frey J.E., Grossniklaus U., and Schlüter P.M. (2022) Low-input high-molecular-weight DNA extraction for long-read sequencing from plants of diverse families. Frontiers in plant Science. 13:883897.

Frachon L., Stirling S.A., F.P. Schiestl & N. Doudareva. (2021) Combining biotechnology and evolution for understanding the mechanisms of pollinator attraction. Current Opinion in Biotechnology. 70: 213-219

Frachon L. (2020) Interaction networks and trait evolution. Report of the 43th New Phytologist Symposium. New Phytologist 226: 644–646

Frachon L, C. Libourel & F. Roux. (2019) Adaptation locale des plantes à un environnement changeant. In book chapter 4: Vivre sous contraintes. In: 101 secrets de l’ADN. D. Faure, D. Joly and S. Salamitou. C.n.r.s. Eds.

Frachon L., B. Mayjonade, C. Bartoli, N.C. Hautekèete & F. Roux. (2019) Adaptation to plant communities across the genome of Arabidopsis thaliana. Molecular Biology Evolution 36: 1442-1456.

Scopece G., Frachon L. & S. Cozzolino. (2019) Do native and invasive herbivores have an effect on Brassica rapa pollination? Plant biology 21: 927-934.

Frachon L.*, C. Bartoli*, S. Carrère, O. Bouchez, A. Chaubet, M. Gautier, D. Roby & F. Roux. (2018) A genomic map of climate adaptation in Arabidopsis thaliana at a micro-geographic scale. Frontiers in Plant Science 9: 967.

Bartoli C.*, Frachon L.*, M. Barret, M. Rigal, C. Huart-Chauveau, B. Mayjonade, C. Zanchetta, O. Bouchez, D. Roby, S. Carrère & F. Roux. (2018) in situ relationships between microbiota and potential pathobiota in Arabidopsis thaliana. The ISME journal 12: 2024-2038.

Frachon L.*, C. Libourel*, R. Villoutreix, S. Carrère, C. Glorieux, C. Huard-Chauveau, M. Navascues, L. Gay, R. Vitalis, E. Baron, L. Amsellem, D. Bouchez, M. Vidal, V. Le Corre, D. Roby, J. Bergelson & F. Roux. (2017) Intermediate degrees of synergistic pleiotropy drive adaptive evolution in ecological time. Nature Ecology and Evolution 1: 1551.

Hautekèete N.C., Frachon L., C. Luczak, B. Toussaint, W. Van Landuyt, F. Van Rossum & Y. Piquot. (2015) Habitat type shapes long-term plant biodiversity budgets in two densely populated regions in north-western Europe. Diversity and Distributions 21: 631-642.

Tayeh A., Hufbauer R.A., Estoup A., Ravigne V., Frachon L. & Facon B. (2015) Biological invasion and biological control select for different life histories. Nature communications 6: 7268.

Liens externes (Links) : 

https://www.researchgate.net/profile/Lea-Frachon https://scholar.google.com/citations?user=wQQs0dAAAAAJ&hl=fr&oi=a